ORIVISE SERVICES
Two ways to work with ORIVISE.
Start from your situation: something isn't working, or you need to decide whether to commit. Each engagement begins with the problem or decision at hand, then defines the evidence and support needed. Programme support for accelerators and university teams is described further down.
Something isn't working
Troubleshooting & R&D leadership.
For diagnostics manufacturers, CDMOs, reagent suppliers and R&D teams with a recurring assay or reagent problem and no specialist time to resolve it.
Troubleshooting Review
A fixed-scope review of your data, methods and history. You receive an assessment of the evidence and most likely causes, a prioritised investigation plan and a decision on what to test next. How the review works →
Reagent & bioconjugation strategy
Focused input on conjugation, reagent behaviour, stability and particle systems where these are driving weak signal, variability or short shelf life.
Fractional R&D leadership
Senior diagnostics R&D leadership for an agreed period: prioritising experiments, interpreting results, leading defined workstreams and mentoring scientific leads. What I lead and own is agreed in writing at the start.
R&D performance & capability support
Help established teams improve technical prioritisation, workflow, team capability and the quality of development decisions.
Typical problems
Where a review usually starts
- Lot-to-lot variation in reagents or calibrators
- Calibrator or control drift over time
- Matrix effects and sample interference
- Conjugate or reagent instability
- Weak signal or high background
- Performance lost at scale-up or transfer
ORIVISE does not run a laboratory. Your team or an agreed laboratory partner runs the experiments; I design, prioritise and interpret them.
Deciding whether to commit
Technical assessment & due diligence.
For funded developers, investors and partners who need an honest view of what the evidence supports before money, a transfer or a partnership is committed.
Feasibility & technical risk review
Review the proposed use, assay approach, data quality and main assumptions. Identify what must be tested before the next investment of time or funding.
Development & transfer readiness
Assess reproducibility, controls, specifications and transfer risks before verification, scale-up or CDMO engagement. Quality system gaps are reviewed where they affect readiness.
Investor technical due diligence
Test whether technical claims are supported by data-room evidence and identify the questions or conditions to resolve before funding or partnership.
Grant and partner evidence planning
Help academic groups and spin-outs identify feasibility gaps, technical work packages and evidence milestones for grant or partner decisions.
What you receive
A written judgement and an evidence plan
- Technical claims mapped against the available evidence.
- Main technical and development risks prioritised.
- Evidence still needed before proceeding.
For investor work, any potential conflict of interest is declared and agreed before work begins, and the fee does not depend on the investment decision.
For accelerators & university programmes
Programme support.
For accelerators, university enterprise teams, biohubs and innovation programmes working with early-stage diagnostics projects. An engagement can combine concept assessment, evidence and risk summaries, mentoring through agreed review points, and help identifying specialist support.
Venture-level findings and any portfolio report are agreed with the programme in advance.
Possible starting point
A scoped pilot
- Select ventures that need a development decision.
- Agree what evidence can be reviewed and what each team needs to know.
- Provide a concise assessment and plan for each team.
- Mentor through one agreed review period.
Number of projects, duration, reporting and fee are agreed for each programme.
Engagements
How engagements are scoped
ORIVISE offers fixed-scope reviews and defined advisory support. Fees depend on the question, the evidence available, urgency, the number of stakeholders and the level of follow-on support required.
Introductory scoping call
No charge.
Focused Troubleshooting Review
Fixed fee agreed in writing before work begins.
Development-readiness or technical-risk review
Quoted after reviewing the decision, the evidence available and the required output.
Fractional R&D leadership or advisory support
Agreed by scope, duration and level of involvement.
A guide price can be shared after the initial scoping conversation.
Not sure which route fits?
Start with the problem or decision in front of you. We can work out the right scope from there.